The Elizabeth River, 23 miles of estuary on the southern end of Chesapeake Bay, has one of the busiest commercial ports in the world. A history of industrial pollution contributed to sediment contamination and “toxic hotspots” along the river. In response, Marjorie Mayfield Jackson helped launch the Elizabeth River Project in 1993 to “restore the river to the highest practical level of environmental quality.” Its 2003 “State of the River” report highlighted a particular hotspot in the southern branch of the river at Money Point, where, for decades, wood treatment facilities allowed creosote to pool on the river floor. This case study tells the story of how Marjorie collaborated with industries, citizens, and governments to spearhead the cleanup of Money Point.