“Manufacturing USA forms public-private, national Institutes that focus on critical advanced manufacturing technology areas with strategic impact on the economy. Through eight Institutes, the Manufacturing USA Program provides matching federal funding to foster networking and mutually beneficial collaboration between key stakeholders (industry, academia, and government) in a ‘whole-of-economy’ approach. … This study found that Manufacturing USA is a valid approach grounded in a portfolio of technology-centric Institutes. The public-private partnership Institute-based model attracts significant and meaningful participation from industry (including large companies and small enterprises), academia, and local, state, and federal government. Institute members have made substantial joint investments in collaborative approaches to R&D and commercialization of cutting-edge advanced manufacturing technologies.”