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“Collaboration between nonprofits and businesses is increasing and becoming more strategically important. Based on 15 case studies, this article presents a cross-sector collaboration framework consisting of four components. First, the collaboration continuum provides a conceptual framework for categorizing different types of partnerships and studying their possible evolution through three principal stages: philanthropic, transactional, and integrative. Second, the collaboration value construct facilitates the analysis of the definition, creation, balance, and renewal of the value generated in different types of alliances. Third, a set of alliance drivers is identified that determines the nature and functioning of the partnerships. Fourth, alliance enablers that contribute to the effective management of the relationship are set forth. The article discusses the dynamics of the alliance marketplace. The research builds on and extends existing interorganizational research theories by providing a distinctive conceptual framework and new empirical understanding of cross-sector alliances. Future research needs are identified.”