“Collaboration is appealing in concept but challenging in practice. While extensive resources … exist online to support collaborative efforts, the fact remains that we human beings are simply not very good at making ‘we’ work. And yet, most changemakers today acknowledge that to address the complex social and environmental challenges we face we must learn how to collaborate — across organizations, sectors, networks, and differences. Effective collaboration must become a reality, not just an aspiration. … Building on the work of many others, we have developed a roadmap that cuts through the complexity. We have tested and refined this framework over years and across domains, and we tend to apply it in the spirit of statistician George Box, who famously said, ‘All models are wrong. Some models are useful.’ We have found it to be useful and hope others will too.”